The Portuguese star, who re-signed for the Red Devils last month from Juventus,
last appeared for the club on 27 May 2009 before joining Real Madrid for £80m.
Cristiano Ronaldo scored 118 goals in 292 appearances in his first spell for Manchester United between 2003-09.
Five-time Ballon d’Or winner Ronaldo is wearing the number seven shirt.
Man Utd
Formation 4-2-3-1
- 1 de Gea
- 29 Wan-Bissaka
- 19 Varane
- 5 Maguire
- 23 Shaw
- 6 Pogba
- 31 Matic
- 11 Greenwood
- 18 Bruno Fernandes
- 25 Sancho
- 7 Cristiano Ronaldo
Substitutes
- 2 Lindelöf
- 3 Bailly
- 8 Mata
- 9 Martial
- 14 Lingard
- 17 Fred
- 20 Dalot
- 22 Heaton
- 34 van de Beek
Newcastle
Formation 5-3-2
- 27 Woodman
- 19 Manquillo
- 14 Hayden
- 6 Lascelles
- 2 Clark
- 11 Ritchie
- 28 Willock
- 36 S Longstaff
- 24 Almirón
- 7 Joelinton
- 10 Saint-Maximin
Substitutes
- 5 Schär
- 12 Lewis
- 16 Hendrick
- 17 Krafth
- 18 Fernández
- 23 Murphy
- 26 Darlow
- 34 Gayle
- 56 White
Referee:Anthony Taylor