Manchester City will hope to welcome back Rodri for the visit of Southampton.
The Premier League champions were without their influential midfielder in the Manchester derby, but did not appear to miss him in a 6-3 win in which the scoreline flattered Manchester United.
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Ilkay Gundogan would likely make way, with Kevin De Bruyne and Bernardo Silva making up the midfield three.
Kyle Walker is out for the foreseeable after undergoing surgery on a groin issue, with his World Cup spot now also under threat,
so Joao Cancelo will continue at right-back as Sergio Gomez gets another chance at left-back.
Ruben Dias missed the derby starting XI so should come in this weekend.
Up front, it will likely be a case of as you were with derby hat-trick heroes Erling Haaland and Phil Foden alongside a Jack Grealish who is really hitting his stride this season.
Manchester City predicted XI:
Ederson;
Cancelo, Dias, Ake, Gomez;
De Bruyne, Rodri, Bernardo;
Foden, Haaland, Grealish
