Manchester United and Chelsea have both been handed defensive injury blows,
in the latest round of Premier League action, with Luke Shaw and Reece James failing to last 45 minutes for their respective clubs on Saturday.
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Two England international full-backs had to be replaced before half-time.
As Ole Gunnar Solskjaer and Thomas Tuchel were forced into tactical and selection tweaks.
The Red Devils and Blues will now be waiting on updates from their medical departments.