Manchester United started their Europa League campaign in Group E with Real Sociedad, FC Sheriff and Omonia Nicosia.
The Red Devils finished second in their group, behind Real Sociedad and had to go into the knockout round play-off as a result.
They faced Barcelona and drew 2-2 in the first leg before winning the second leg and going through 4-3 on aggregate.
Following their play-off win, United were drawn against Real Betis in the round of 16.
They won the first leg 4-1 and advanced after a 5-1 victory on aggregate.
And now Manchester United draw Another team from Spain Sevilla in the Quater final of Europa League
The two teams played in the final of the 2020 Europa League, with the Spanish side emerging triumphant 2-1.
If United get through the last eight, they could face Juventus in the semi-finals, with the Italian giants drawn against Sporting CP of Portugal who knocked out Arsenal on Thursday.
EUROPA LEAGUE QUARTER-FINAL DRAW
Manchester United v Sevilla
Bayer Leverkusen v Union Saint-Gilloise
Juventus v Sporting CP
Feyenoord v Roma
EUROPE LEAGUE SEMI-FINAL DRAW
Juventus or Sporting CP v Manchester United or Sevilla
Feyenoord or Roma v Bayer Leverkusen or Union Saint-Gilloise